Mister is a space‑faring outlaw, known as a “coyote,” who has spent a year in prison for a traffic offence. Ten days before his scheduled release, he escapes with the help of his former partners Bishop and Katana. He then looks for Franka, a young woman left under his care after her father’s death, and takes her on a quest to locate her father’s treasure. Pursuing them are federal investigators Angelica and Chelsea, along with the android assassins known as Madame Marciano’s Twelve Sisters of the Criminal Guild.