Darkside Blues follows a world dominated by the Persona Century Corporation, which has acquired almost every parcel of land on Earth. Dissent is not tolerated within the corporation, and those who oppose Persona are dealt with swiftly. The free town of Kabuki‑cho, known as “The Dark Side of Tokyo”, remains one of the few places still outside Persona’s control. Within this town, a small resistance group called Messiah is led by a woman named Mai. Into this world steps a man who goes by the nickname Darkside. Sealed in another dimension eighteen years ago by Persona Century, Darkside returns to aid Messiah with his unique mystic power of renewal.