Kimi ga Aruji de Shitsuji ga Ore de follows Ren Uesugi and his sister Mihato after a family crisis forces them to leave home. Struggling with poverty in the city, they eventually find employment as servants in the Kuonji family mansion, serving the three sisters, Shinra, Miyu, and Yume. Through this role, Ren becomes acquainted with the other house staff and the sisters’ acquaintances.