Vash the Stampede is a walking contradiction: the most wanted outlaw on the desert planet Gunsmoke, with a bounty of $$60$ billion, yet a pacifist who loves doughnuts and abhors violence. As he wanders with two persistent insurance agents, Meryl and Milly, they discover the man behind the myth is a gentle soul, haunted by a mysterious past.
Their journey turns deadly when a crew of legendary assassins, led by the fanatical priest Nicholas D. Wolfwood, is hired to collect Vash's bounty. This forces the fugitive into a brutal conflict where his unwavering vow never to kill is tested against overwhelming, genocidal threats.
The series peels back the layers of Vash’s tragic history, revealing he is a powerful, engineered being with a direct link to the planet’s near-destruction. His ultimate struggle is not for survival, but to uphold his ideals of peace and love in a world determined to force him into the role of a destructive god.