Vash the Stampede carries a $60,000,000,000 bounty on his head, earning him the nickname “The Humanoid Typhoon.” Though rumors paint him as a ruthless villain who destroys cities for sport, Vash is actually a gentle soul who claims never to have taken a life and strives to avoid violence at all costs. He wanders the desert world of Gunsmoke with his fondness for doughnuts and a carefree attitude, while two insurance agents, Meryl Stryfe and Milly Thompson, try to protect the public from the chaos surrounding him. Their misadventures soon turn deadly as a group of legendary assassins is summoned to exact vengeance on the trio. As the story unfolds, Vash’s painful past is revealed, pushing his morals and principles to their limits.